| Hemmer- und Induktoren von CYP-450
Cytochromen |
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- idR erniedrigte
Bioverfügbarkeit der betroffenen
Medikamente! |
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1A2 |
2C9 |
2C19 |
2D6 |
2E1 |
3A4 |
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| betroffene Medikamente (noch
einordnen: Digitoxin)
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Theophyllin |
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Terfenadin |
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orale
Antikoagulantien |
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ð |
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unzureichende
Thromboseprophyllaxe |
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|
orale
Kontrazeptiva |
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ð |
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unsichere
Kontrazeption |
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Glukokortikoide |
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Theophyllin |
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Terfenadin |
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| • |
|
orale
Antikoagulantien |
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ð |
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unzureichende
Thromboseprophyllaxe |
| • |
|
orale
Kontrazeptiva |
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ð |
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unsichere
Kontrazeption |
| • |
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Glukokortikoide |
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Methadon |
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| Antiepileptika |
Barbiturate
(zB Phenobarbital) |
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| Phenytoin |
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| Carbamazepin |
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| Antibiotika |
Rifampicin |
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| Isoniazid |
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| Tabak, Teer: Rauchen! |
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| Johanniskraut |
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| Alkohol |
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| klinisch relevante
Hemmer
der CYP-450 |
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- idR erhöhte
Bioverfügbarkeit der betroffenen
Medikamente! |
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1A2 |
2C9 |
2C19 |
2D6 |
2E1 |
3A4 |
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| betroffene Medikamente (noch
einordnen: orale Antidiabetika, Phenytoin?,
Carbamazepin?)
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| • |
|
Theophyllin |
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| • |
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Terfenadin |
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| • |
|
orale
Antikoagulantien |
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ð |
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verstärkte
Blutungsneigung |
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| • |
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Theophyllin |
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ð |
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Intox.-Gefahr |
| • |
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Terfenadin |
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| • |
|
orale
Antikoagulantien |
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ð |
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verstärkte
Blutungsneigung |
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| Makrolide |
Erythromycin |
Erythrocin® |
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| Roxithromycin |
Rulid |
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| Clarithromycin
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Klacid® |
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| Josamycin |
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| Azole |
Itraconazol |
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| Ketokonazol |
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Omeprazol |
Antramups® |
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| Chinolone |
Ciprofloxacin |
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| Norfloxacin |
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| Statine |
Simvastatiin |
Zocor |
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| Fluvastatin |
Lescol |
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| Antiarrhythmika |
Chinidin |
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| Amiodaron |
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| Ca-Antagonisten |
Diltiazem |
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| Verapamil |
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| Serotonin-Reuptake-Inhibitoren |
Fluvoxamin |
Floxyfral |
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| Fluoxetin |
Fluctine |
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| Paroxetin |
Deroxat |
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| Nefazodon |
Nefadar |
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| HIV-Protease-Inhibitoren |
Ritonavir |
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Disulfiram |
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| quellen |
verlauf |
links |
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| •1 |
|
Pharmaskript Prof.
Lauterburg, Unibe, S. 6 (Hemmer- und
Induktoren) bezw. S.5 |
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| •2 |
|
x |
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| •3 |
|
x |
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| •4 |
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x |
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| begonnen |
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20.06.04 |
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| aktualisiert: |
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07.08.04 |
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(Omeprazol) |
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08.08.04 |
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(Methadon) |
| broken links: |
|
20.06.04 |
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| rückmeldungen
via emaille |
| legende / farbcode |
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